Pymss Studio is a cross-platform desktop application that turns the pymss music source separation engine into a complete, GUI-driven workflow for producers, researchers, and audio editors. Instead of running source separation from the command line, users get a workspace dashboard showing runtime health, local model status, and job history; a separation setup screen for importing audio/video files or folders and choosing models, output format, runtime device, and TTA settings; a task queue with stage-level progress, retries, and logs; a model library for browsing and downloading separation models; and a built-in stem editor with waveform preview, mixing controls, and export. The app is built with Tauri v2 and Rust for the desktop shell, a Vue 3/TypeScript frontend, and a Python worker that drives the external pymss core package, with prebuilt packages for Windows (CPU/CUDA/ROCm), macOS (Apple Silicon via MLX), and Linux.